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Next-Generation Biomarkers for Early Detection of CKDu

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Chronic Kidney Disease of uncertain etiology (CKDu) is considered unresolved environmental nephropathy. CKDu is still increasing rapidly and gaining much attention all over the world. In Sri Lanka, CKDu has been reported to be common and increasing in prevalence. Furthermore, it is widely reported in geographically discrete regions of North Central and North Western provinces […]

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Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka

Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka?

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Shakila Premarathne 1, Rohana Chandrajith 2, Nishantha Nanayakkara 3, C D Gamage 4, Neelakanthi Ratnatunga 5, Sulochana Wijetunge 5, Zeid Badurdeen 6, Shashika Guruge 7, N Elladeniya 6, K P S Madushan 6, K O C U Samarasiri 6, Pasan Hewavitharane 1, Dulanjali Herath 1, Sachintha Senarathne 8 Affiliations Centre for Research, National Hospital, Kandy,

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Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka? Read More »

Pilot Study of Renal Urinary Biomarkers for Diagnosis of CKD of Uncertain Etiology

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Buddhi N.T.W. Fernando1,7 , Asfa Alli-Shaik2,7 , Rusiru K.D. Hemage1 , Zeid Badurdeen1 , Thilini W. Hettiarachchi1 , Hemalika T.K. Abeysundara3 , Thilak D.J. Abeysekara1 , Abdul Wazil4 , Saman Rathnayake5 , Jayantha Gunaratne2,6 and Nishantha Nanayakkara4   1 Centre for Education, Research and Training on Kidney Diseases (CERTKiD), Faculty of Medicine, University of Peradeniya,

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Prospective Biopsy-Based Study of CKD of Unknown Etiology in Sri Lanka

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Shuchi Anand,1 Maria E. Montez-Rath,1 Dinuka Adasooriya,2,3 Neelakanthi Ratnatunga,4 Neeraja Kambham,5 Abdool Wazil,2 Sulcohana Wijetunge,4 Zeid Badurdeen,3 Charaka Ratnayake,2 Nishamani Karunasena,2 Stephen L. Schensul,6 Penny Valhos,7 Lalarukh Haider,8 Vivek Bhalla,1 Adeera Levin,9 Paul H. Wise,10 Glenn M. Chertow,1 Michele Barry,11 Andrew Z. Fire,5 and Nishantha Nanayakkara2,3   1 Division of Nephrology and Departments of 5

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Screening for chronic kidney disease of uncertain aetiology in Sri Lanka: usability of surrogate biomarkers over dipstick proteinuria

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Samantha Ratnayake1,2*, Zeid Badurdeen1 , Nishantha Nanayakkara3 , Tilak Abeysekara1 , Neelakanthi Ratnatunga4 and Ranjith Kumarasiri5   Abstract Background: The use of dipstick proteinuria to screen Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a recently debated matter of dispute. The aim of this study was to assess the suitability of biomarkers:

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Epidemiology, molecular, and genetic methodologies to evaluate causes of CKDu around the world: report of the Working Group from the ISN International Consortium of Collaborators on CKDu

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Shuchi Anand1 , Ben Caplin2 , Marvin Gonzalez-Quiroz2,3 , Stephen L. Schensul4 , Vivek Bhalla1 , Xavier Parada5 , Nishantha Nanayakkara6 , Andrew Fire1 , Adeera Levin7 and David J. Friedman8 , on behalf of International Society of Nephrology’s International Consortium of Collaborators on Chronic Kidney Disease of Unknown Etiology (i3C)9   1 School of Medicine,

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Prevalence, risk factors and predicted risk of cardiac events in chronic kidney disease of uncertain aetiology in Sri Lanka: A tubular interstitial nephropathy

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Thilini W. Hettiarachchi1 *, Buddhi N. T. W. Fernando2 , Thilini Sudeshika3 , Zeid Badurdeen1 , Shuchi Anand4 , Ajith Kularatne5 , Sulochana Wijetunge6 , Hemalika T. K. Abeysundara7 , Nishantha Nanayakkara8 1 Centre for Education, Research and Training on Kidney Diseases (CERTKiD), Faculty of Medicine, University of Peradeniya, Galaha, Sri Lanka. 2 Department of

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Chronic Kidney Disease of Uncertain Etiology in Sri Lanka is a Possible Sequel of Interstitial Nephritis!

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Zeid Badurdeen1, Nishantha Nanayakkara1,4, Neelakanthi V.I. Ratnatunga1,2, Abdul W.M. Wazil4, Tilak D.J. Abeysekera1, Premil N. Rajakrishna4, Jalitha P. Thinnarachchi4, Ranjith Kumarasiri3, Dulani D. Welagedera4, Needika Rajapaksha4, and Adambarage P.D. Alwis4 1Centre for Education Research and Training on Kidney Diseases (CERTKiD), < 2Department of Pathology, 3Department of Community Medicine, Faculty of Medicine, University of Peradeniya, Peradenya.

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Expanding CAPD In Low-Resource Settings: A Distance Learning Approach

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Robert Rope1,* , Nishantha Nanayakkara2,* , Abdul Wazil2, Sewmini Dickowita2, Rajitha Abeyeskera2, Lishanthe Gunerathne3, Dinuka Adoosoriya2, Nishamani Karunasena2, Chrarake Rathnayake2, Shuchi Anand1, and Anjali Saxena1,4 1Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA USA 2Teaching Hospital, Kandy, Sri Lanka; Renal Care & Research Unit 3Girandurukotte, Sri Lanka 4Division of Nephrology, Santa Clara

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Overcoming barriers and building a strong peritoneal dialysis programme – Experience from three South Asian countries.

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Klara Paudel1, Ahad Qayyum2, Abdul WM Wazil3, Sanjib K Sharma4, Kalpana Shrestha5, Stanley Fan6, Agnes Haris7, Fredric O Finkelstein8, Nishanthe Nanayakkara3 1Department of Medicine, Charak Memorial Hospital, Pokhara, Nepal 2Department of Nephrology, Bahria Town Hospital, Lahore, Pakistan 3Department of Nephrology, Teaching Hospital, Kandy, Sri Lanka 4Department of Internal Medicine, BP Koirala Institute of Health Sciences,

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