CKDu

Challenges and opportunities in interventions for chronic kidney disease of unknown origin (CKDu): report from the International Society of Nephrology Consortium of Collaborators on CKDu

Challenges and opportunities in interventions for chronic kidney disease of unknown origin (CKDu): report from the International Society of Nephrology Consortium of Collaborators on CKDu Brendan Smyth1,2 , Jason Glaser3 , Jaime Butler-Dawson4,5 , Nishantha Nanayakkara6 , David H. Wegman3,7 , Shuchi Anand8 and Adeera Levin9 1 National Health and Medical Research Council (NHMRC) Clinical …

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Early ultrastructural changes in biopsies from patients with symptomatic CKDu (Sym-CKDu)

Christoph Daniel, Prof.1 ; Philipp Enghard, PD2 ; Neelakanthi Ratnatunga, Prof.3  ; Sulochana Wijetunge, Prof. 3 ; Wazil AWM, MD7 ; Christian Zwiener, Prof. 4 ; Johannes A.C. Barth, Prof.5 ; Rohana Chandrajith, Prof.6 ; Monika Klewer1 ; Kai-Uwe Eckhardt, Prof.2 , Kerstin Amann, Prof.1 ; Paul Freund, MD2 , Shakila Premarathne8 , W.D.R.N. Pushpakumara, …

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Risk factors and their effect on the progression of Sri Lankan CKDu

MGIH Bandara1, SWMPWCIB Weerakoon1, HMDK Herath1, HPNS Hewapathirane1, HGN Erandika1, HPM Hewavitharana1, N Nanayakkara2 1Department of NEPHROLOGY, Centre For Research National Hospital Kandy, Sri Lanka 2Department of Nephrology, National Hospital Kandy, Sri Lanka Objectives: We focused on risk factors like family history, social support for patients, alcoholic beverage consumption, tobacco use, etc. in CKDu to …

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Familial Clustering in Sri Lankan CKDu cases

MGIH BANDARA1, SWMPWCIB WEERAKOON1, HMDK HERATH1, HPM HEWAVITHARANE1, HPNS HEWAPATHIRANE1, HGN ERANDIKA1, N NANAYAKKARA2 1Department of NEPHROLOGY, Centre For Research – National Hospital Kandy, Sri Lanka 2Department of Nephrology, National Hospital Kandy, Sri Lanka Objectives: This study has explored familial aggregation patterns in Sri Lankan CKDu patients related to the onset and course of the …

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Next-Generation Biomarkers for Early Detection of CKDu

Chronic Kidney Disease of uncertain etiology (CKDu) is considered unresolved environmental nephropathy. CKDu is still increasing rapidly and gaining much attention all over the world. In Sri Lanka, CKDu has been reported to be common and increasing in prevalence. Furthermore, it is widely reported in geographically discrete regions of North Central and North Western provinces …

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Chronic kidney disease of unknown aetiology mostly claims young male farmers: Uva study

Chronic kidney disease of unknown aetiology mostly claims young male farmers: Uva study

Finds cause of death to be end-stage renal disease Recommends urgent interventions to prevent disease progression BY Ruwan Laknath Jayakody The main cause of death in chronic kidney disease of unknown aetiology (CKDu) patients in a study that assessed a sample population from the Badulla District in the Uva Province, among whom the majority were …

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Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka

Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka?

Shakila Premarathne 1, Rohana Chandrajith 2, Nishantha Nanayakkara 3, C D Gamage 4, Neelakanthi Ratnatunga 5, Sulochana Wijetunge 5, Zeid Badurdeen 6, Shashika Guruge 7, N Elladeniya 6, K P S Madushan 6, K O C U Samarasiri 6, Pasan Hewavitharane 1, Dulanjali Herath 1, Sachintha Senarathne 8 Affiliations Centre for Research, National Hospital, Kandy, …

Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka? Read More »

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Pilot Study of Renal Urinary Biomarkers for Diagnosis of CKD of Uncertain Etiology

Buddhi N.T.W. Fernando1,7 , Asfa Alli-Shaik2,7 , Rusiru K.D. Hemage1 , Zeid Badurdeen1 , Thilini W. Hettiarachchi1 , Hemalika T.K. Abeysundara3 , Thilak D.J. Abeysekara1 , Abdul Wazil4 , Saman Rathnayake5 , Jayantha Gunaratne2,6 and Nishantha Nanayakkara4   1 Centre for Education, Research and Training on Kidney Diseases (CERTKiD), Faculty of Medicine, University of Peradeniya, …

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Prospective Biopsy-Based Study of CKD of Unknown Etiology in Sri Lanka

Shuchi Anand,1 Maria E. Montez-Rath,1 Dinuka Adasooriya,2,3 Neelakanthi Ratnatunga,4 Neeraja Kambham,5 Abdool Wazil,2 Sulcohana Wijetunge,4 Zeid Badurdeen,3 Charaka Ratnayake,2 Nishamani Karunasena,2 Stephen L. Schensul,6 Penny Valhos,7 Lalarukh Haider,8 Vivek Bhalla,1 Adeera Levin,9 Paul H. Wise,10 Glenn M. Chertow,1 Michele Barry,11 Andrew Z. Fire,5 and Nishantha Nanayakkara2,3   1 Division of Nephrology and Departments of 5 …

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