biomarkers

 Sonographically determined kidney measurements are better able to predict histological changes and a low CKD-EPI eGFR when weighted towards cortical echogenicity

 Introduction: – Renal ultrasound is commonly used to assess chronic kidney disease (CKD) patients. Some sonographic parameters like kidney length, cortical echogenicity, and cortical thickness correlate with renal function. – However, the accuracy of these crude parameters is limited. Weighting them towards cortical echogenicity may improve their ability to detect renal dysfunction and histological changes. […]

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Screening for chronic kidney disease of uncertain aetiology in Sri Lanka: usability of surrogate biomarkers over dipstick proteinuria

Samantha Ratnayake1,2*, Zeid Badurdeen1 , Nishantha Nanayakkara3 , Tilak Abeysekara1 , Neelakanthi Ratnatunga4 and Ranjith Kumarasiri5   Abstract Background: The use of dipstick proteinuria to screen Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a recently debated matter of dispute. The aim of this study was to assess the suitability of biomarkers:

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POTENTIAL BIOMARKERS FOR CKD-U PATIENTS IN SRILANKA: A REVIEW

Fernando,W.B.N.T1., Hettiarachchi, T.W1., Hemage,R1., Badurdeen, M.Z1., Nanayakkara, N2* 1Centre for Education, Research and Training on Kidney Diseases (CERTKiD), Faculty of Medicine, University of Peradeniya, Sri Lanka 2Transplant and Dialysis Unit, Teaching Hospital, Kandy, Sri Lanka   Background: Chronic Kidney Disease due to unknown etiology (CKD-u) is a deadly disease. Its prevalence has been described in

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