Abstracts

Socio-economic determinants of Chronic Kidney Diseases of uncertain aetiology (CKDu)

  Introduction: – Presents the background and context of CKDu in Sri Lanka and globally. Highlights that CKDu is increasing in Uva Province but socio-economic risk factors are unknown. – Concisely states the study objectives to identify socio-economic risk factors for CKDu in Uva Province using statistical models. Methods: – Appropriate cross-sectional study design with […]

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Describing Natural History and Exploring Risk Factors for Kidney Function Decline in Persons With CKD of Uncertain Etiology in Sri Lanka.

Pasan Hewavitharana1,2,11, Stephen Schensul3 , Edison Lee4 , Maria Montez-Rath4 , Sachintha Senarathne5 , Sai Liu4 , Kaitlin Harold4 , Santhushya Hewapathiranage1 , Naduni Erandika1 , Hemalika T.K. Abeysundara6 , Xue Yu4 , Vivek Bhalla4 , Andrew Fire7 , Adeera Levin8 , Shuchi Anand4 , Penny Vlahos9,11, Rohana Chandrajith5,11 and Nishantha Nanayakkara1,10,11 1 Center for

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Describing Natural History and Exploring Risk Factors for Kidney Function Decline in Persons With CKD of Uncertain Etiology in Sri Lanka. Read More »

The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation.

The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation. Kalpa Dheerasekara 1, Rekshi Tharanga 1, Lakmali Rajamanthri 2, Abdul Wazil 3, Nishantha Nanayakkara 3, Rohitha Muthugala 2 1Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka. 2Department of Virology,

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The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation. Read More »

Urinary MicroRNA Analysis Indicates an Epigenetic Regulation of Chronic Kidney Disease of Unknown Etiology in Sri Lanka.

Urinary MicroRNA Analysis Indicates an Epigenetic Regulation of Chronic Kidney Disease of Unknown Etiology in Sri Lanka. Thanuri Edirithilake 1, Nishantha Nanayakkara 2, Xiao Xiao Lin 3, Patrick J Biggs 4 5, Rohana Chandrajith 6, Sampath Lokugalappatti 1, Saumya Wickramasinghe 1 7 1 Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine and Animal Science,

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Urinary MicroRNA Analysis Indicates an Epigenetic Regulation of Chronic Kidney Disease of Unknown Etiology in Sri Lanka. Read More »

Leptospirosis: A Potential Culprit for Chronic Kidney Disease of Uncertain Etiology

Leptospirosis: A Potential Culprit for Chronic Kidney Disease of Uncertain Etiology Premarathne S.S.a,b · Gamage C.b · Chandrajith R.c · Ratnatunge N.V.d · Wijetunge S.d · Wazil A.e · Chou L.-F.f · Ko Y.-C.f · Huang C.-T.f · Yang H.-Y.f,g,h · Fonseka A.b · Sonnadara T.a · Herath D.a · Hewavitharane P.a · Yang C.-W.f,g,h

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Hantavirus infection as a risk factor for chronic kidney disease of unknown aetiology (CKDu) and its prevalence in endemic areas of Sri Lanka since 2010 according to a retrospective serological analysis

Hantavirus infection as a risk factor for chronic kidney disease of unknown aetiology (CKDu) and its prevalence in endemic areas of Sri Lanka since 2010 according to a retrospective serological analysis Chandika D. Gamage1​, Shanika Nanayakkara2​,3​, Yomani D. Sarathkumara1​,4​, Devinda S. Muthusinghe5​,6​, Kenta Shimizu7​, Jiro Arikawa7​, Sithumini M. W. Lokupathirage5​,6​, Nishantha Nanayakkara8​, Lishanthe Gunarathne9​, Rohana

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Hantavirus infection as a risk factor for chronic kidney disease of unknown aetiology (CKDu) and its prevalence in endemic areas of Sri Lanka since 2010 according to a retrospective serological analysis Read More »

Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology.

Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology. Zeid Badurdeen, Neelakanthi Ratnatunga, Tilak Abeysekera, Abdul. W. M. Wazil, Premil N. Rajakrishna, Jalitha P. Thinnarachchi, Dulani D. Welagedera, Nadeeka Ratnayake, Adambarage. P. D. Alwis, Hemalika Abeysundara, Ranjith Kumarasiri, Richard Taylor & Nishantha Nanayakkara   Abstract Background Patients presenting

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Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology. Read More »

Point prevalence of chronic kidney disease of uncertain etiology in a suspected endemic region determined using predefined cutoffs for markers of kidney disease: a pilot study

Point prevalence of chronic kidney disease of uncertain etiology in a suspected endemic region determined using predefined cutoffs for markers of kidney disease: a pilot study. Zeid Badurdeen1 , Tilak D.J. Abeysekera1 , Lishantha Gunaratne2 , Samantha Ratnayake3 , Neelakanthi V.I. Ratnatunga4 and Nishantha Nanayakkara5 1 Center for Education Research and Training on Kidney Diseases

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Point prevalence of chronic kidney disease of uncertain etiology in a suspected endemic region determined using predefined cutoffs for markers of kidney disease: a pilot study Read More »

Factors Associated with Symptom Burden in Adults with Chronic Kidney Disease Undergoing Hemodialysis: A Prospective Study

Factors Associated with Symptom Burden in Adults with Chronic Kidney Disease Undergoing Hemodialysis: A Prospective Study. Thalwaththe Gedara Nadeeka Shayamalie Gunarathne,1,2 Li Yoong Tang,1,* Soo Kun Lim,3 Nishantha Nanayakkara,4 Hewaratne Dassanayakege Wimala Thushari Damayanthi,2 and Khatijah L. Abdullah5 1 Department of Nursing Science, Faculty of Medicine, University Malaya, Kuala Lumpur 50603, Malaysia; [email protected] or [email protected]

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Factors Associated with Symptom Burden in Adults with Chronic Kidney Disease Undergoing Hemodialysis: A Prospective Study Read More »

Comparison of biochemical characteristics between an endemic and a nonendemic area for CKDu Sri Lanka

Comparison of biochemical characteristics between an endemic and a nonendemic area for CKDu Sri Lanka. A Medagedara1, Pasan Hewavitharane2, Rohana Chandrajith3, Hemalika T K. Abeysundara4, RO Thatil5, S Thennakoon6, Buddhisha Mahanama2, N Weerasuriya7, A Thilakarathne7, Nishantha Nanayakkara2 1 Center for Research, National Hospital, Kandy; Department of Fundamentals of Nursing, Faculty of Nursing, University of Colombo,

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