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English Articles

Review of Urinary proteomics in chronic kidney disease: diagnosis and risk of progression beyond albuminuria

Summary This study examined the utility of urinary proteomics analysis using capillary electrophoresis coupled to mass spectrometry (CE-MS) for diagnosing chronic kidney disease (CKD) and predicting rapid kidney function decline. The authors analyzed urine samples from 18 CKD patients (including those with hypertensive nephropathy) and 17 healthy controls. They found that a urinary proteomic classifier […]

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Association Between Occupational Heat Stress and Kidney Disease Among 37,816 Workers in the Thai Cohort Study (TCS)

Introduction – Provides background on the rising issue of heat stress due to climate change and its potential health impacts, including kidney disease. – Highlights the lack of studies examining the association between occupational heat stress and kidney disease, particularly in tropical countries like Thailand. – Outlines the objectives of the study to examine this

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The relationship between hydronephrosis severity on ultrasound and kidney stone size

Introduction Kidney stones are a common urologic condition, with an increasing incidence and prevalence globally. Non-contrast computed tomography (CT) is frequently used in emergency departments to evaluate suspected kidney stones, given its high accuracy for detecting the presence, size and location of stones. However, ultrasound is advantageous due to lower cost, lack of ionizing radiation,

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Critical Review of Glutathione level and glutathione reductase activity in serum of coronary heart disease patients

This study by Zuzak et al. investigates glutathione reductase (GR) activity and glutathione (GSH) levels in the serum of patients with different stages of coronary heart disease (CHD). The authors enrolled 20 patients, each with stable angina, unstable angina, and myocardial infarction, along with 20 healthy controls. Blood samples are collected before cardiac catheterization. GR

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Critical Review of Near-Death Experiences and the Temporal Lobe by Britton and Bootzin (2004)

Summary of the Study This study investigated the hypothesis that near-death experiences are associated with altered temporal lobe functioning. Their study compared 23 individuals reporting transcendental near-death experiences during life-threatening events with 20 healthy control subjects on measures of temporal lobe functioning, including EEG during an overnight sleep study, questionnaires on temporal lobe symptoms, and

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Association between pesticide exposure and chronic kidney disease of uncertain etiology in agricultural worker populations: A systematic review and meta-analysis

This proposed systematic review would compile evidence on the relationship between pesticide exposure and CKDu risk specifically in agricultural worker groups through meta-analysis of observational studies. It can evaluate the strength of association and sources of heterogeneity across different geographical regions and help identify research gaps to drive priorities for future epidemiological research on environmental/occupational

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Inside the bold mission to map every immune system in the world

Introduction The article “Inside the bold mission to map every immune system in the world” by James Lloyd, published in BBC Science Focus Magazine in January 2024, discusses the aims and challenges of the Human Immunome Project (HIP), a global initiative that seeks to create a digital library of the immune system of every human

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Critical review of the article on ‘Limited Health Literacy in Advanced Kidney Disease’

Citation: Taylor, D. M., Bradley, J. A., Bradley, C., Draper, H., Johnson, R., Metcalfe, W., … & ATTOM Investigators. (2016). Limited health literacy in advanced kidney disease. Kidney international, 90(3), 685-695. Introduction This study aimed to determine the prevalence of limited health literacy and its associations in patients with advanced kidney disease in the UK.

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Socio-economic determinants of Chronic Kidney Diseases of uncertain aetiology (CKDu)

  Introduction: – Presents the background and context of CKDu in Sri Lanka and globally. Highlights that CKDu is increasing in Uva Province but socio-economic risk factors are unknown. – Concisely states the study objectives to identify socio-economic risk factors for CKDu in Uva Province using statistical models. Methods: – Appropriate cross-sectional study design with

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Kidney Stones: A Potential Indicator of Fracture Risk in Chronic Kidney Disease

Introduction This study investigates the association between kidney stones and the risk of osteoporotic fracture in patients with chronic kidney disease (CKD). The introduction provides background on how CKD patients have a higher risk of osteoporotic fracture compared to the general population, and how bone mineral density alone has limitations in predicting fracture risk. The

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