CKDu. Sri Lanka

Potential diagnostic biomarkers for chronic kidney disease of unknown etiology (CKDu) in Sri Lanka: a pilot study

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Critical Review Introduction The study by Sayanthooran et al. (2017) explores a significant public health issue in Sri Lanka—chronic kidney disease of unknown etiology (CKDu)—which predominantly affects farming communities in dry zones. Unlike typical CKD cases, which are often linked to diabetes or hypertension, CKDu lacks a clearly defined cause. The researchers aimed to identify […]

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 Sonographically determined kidney measurements are better able to predict histological changes and a low CKD-EPI eGFR when weighted towards cortical echogenicity

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 Introduction: – Renal ultrasound is commonly used to assess chronic kidney disease (CKD) patients. Some sonographic parameters like kidney length, cortical echogenicity, and cortical thickness correlate with renal function. – However, the accuracy of these crude parameters is limited. Weighting them towards cortical echogenicity may improve their ability to detect renal dysfunction and histological changes.

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 Sonographically determined kidney measurements are better able to predict histological changes and a low CKD-EPI eGFR when weighted towards cortical echogenicity Read More »

Association Between Occupational Heat Stress and Kidney Disease Among 37,816 Workers in the Thai Cohort Study (TCS)

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Introduction – Provides background on the rising issue of heat stress due to climate change and its potential health impacts, including kidney disease. – Highlights the lack of studies examining the association between occupational heat stress and kidney disease, particularly in tropical countries like Thailand. – Outlines the objectives of the study to examine this

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The relationship between hydronephrosis severity on ultrasound and kidney stone size

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Introduction Kidney stones are a common urologic condition, with an increasing incidence and prevalence globally. Non-contrast computed tomography (CT) is frequently used in emergency departments to evaluate suspected kidney stones, given its high accuracy for detecting the presence, size and location of stones. However, ultrasound is advantageous due to lower cost, lack of ionizing radiation,

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Association between pesticide exposure and chronic kidney disease of uncertain etiology in agricultural worker populations: A systematic review and meta-analysis

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This proposed systematic review would compile evidence on the relationship between pesticide exposure and CKDu risk specifically in agricultural worker groups through meta-analysis of observational studies. It can evaluate the strength of association and sources of heterogeneity across different geographical regions and help identify research gaps to drive priorities for future epidemiological research on environmental/occupational

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Socio-economic determinants of Chronic Kidney Diseases of uncertain aetiology (CKDu)

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  Introduction: – Presents the background and context of CKDu in Sri Lanka and globally. Highlights that CKDu is increasing in Uva Province but socio-economic risk factors are unknown. – Concisely states the study objectives to identify socio-economic risk factors for CKDu in Uva Province using statistical models. Methods: – Appropriate cross-sectional study design with

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Chronic kidney disease of unknown aetiology mostly claims young male farmers: Uva study

Chronic kidney disease of unknown aetiology mostly claims young male farmers: Uva study

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Finds cause of death to be end-stage renal disease Recommends urgent interventions to prevent disease progression BY Ruwan Laknath Jayakody The main cause of death in chronic kidney disease of unknown aetiology (CKDu) patients in a study that assessed a sample population from the Badulla District in the Uva Province, among whom the majority were

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The Medical Mystery continues........ Wilgamuwa the newest hotspot of CKDu in Sri Lanka

The Medical Mystery continues……. Wilgamuwa the newest hotspot of CKDu in Sri Lanka?

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Chronic kidney disease of uncertain etiology (CKDu) or Rajarata kidney disease is a progressive disease that causes irreversible kidney failure and eventually death. Unlike chronic kidney diseases (CKD), which in most cases are linked to known causes such as, hypertension, diabetes, and chronic glomerular nephritis, the causative factors of this mysterious disease are obscure. Over

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Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

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Shanika Nanayakkaraa,b,⁎,1,  S.T.M.L.D. Senevirathnac,1, Kouji H. Haradad, Rohana Chandrajithe, Toshiaki Hitomif, Tilak Abeysekerag, Eri Musoh, Takao Watanabei, Akio Koizumij   Affiliations a. School of Dentistry, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia b. Institute of Dental Research, Westmead Centre for Oral health, Westmead Hospital, Westmead, Australia c. CSU Engineering, Faculty of Business,

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