CKDu
Risk factors and their effect on the progression of Sri Lankan CKDu
MGIH Bandara1, SWMPWCIB Weerakoon1, HMDK Herath1, HPNS Hewapathirane1, HGN Erandika1, HPM Hewavitharana1, N Nanayakkara2 1Department of NEPHROLOGY, Centre For Research National Hospital Kandy, Sri Lanka 2Department of Nephrology, National Hospital Kandy, Sri Lanka Objectives: We focused on risk factors like family history, social support for patients, alcoholic beverage consumption, tobacco use, etc. in CKDu to
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Familial Clustering in Sri Lankan CKDu cases
MGIH BANDARA1, SWMPWCIB WEERAKOON1, HMDK HERATH1, HPM HEWAVITHARANE1, HPNS HEWAPATHIRANE1, HGN ERANDIKA1, N NANAYAKKARA2 1Department of NEPHROLOGY, Centre For Research – National Hospital Kandy, Sri Lanka 2Department of Nephrology, National Hospital Kandy, Sri Lanka Objectives: This study has explored familial aggregation patterns in Sri Lankan CKDu patients related to the onset and course of the
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Next-Generation Biomarkers for Early Detection of CKDu
Chronic Kidney Disease of uncertain etiology (CKDu) is considered unresolved environmental nephropathy. CKDu is still increasing rapidly and gaining much attention all over the world. In Sri Lanka, CKDu has been reported to be common and increasing in prevalence. Furthermore, it is widely reported in geographically discrete regions of North Central and North Western provinces
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Chronic kidney disease of unknown aetiology mostly claims young male farmers: Uva study
Finds cause of death to be end-stage renal disease Recommends urgent interventions to prevent disease progression BY Ruwan Laknath Jayakody The main cause of death in chronic kidney disease of unknown aetiology (CKDu) patients in a study that assessed a sample population from the Badulla District in the Uva Province, among whom the majority were
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Could Consumption of Trace Element–Contaminated Rice Be a Risk Factor for Acute Interstitial Nephritis with Uncertain Etiology in the Dry Zone of Sri Lanka?
Shakila Premarathne 1, Rohana Chandrajith 2, Nishantha Nanayakkara 3, C D Gamage 4, Neelakanthi Ratnatunga 5, Sulochana Wijetunge 5, Zeid Badurdeen 6, Shashika Guruge 7, N Elladeniya 6, K P S Madushan 6, K O C U Samarasiri 6, Pasan Hewavitharane 1, Dulanjali Herath 1, Sachintha Senarathne 8 Affiliations Centre for Research, National Hospital, Kandy,
Pilot Study of Renal Urinary Biomarkers for Diagnosis of CKD of Uncertain Etiology
Buddhi N.T.W. Fernando1,7 , Asfa Alli-Shaik2,7 , Rusiru K.D. Hemage1 , Zeid Badurdeen1 , Thilini W. Hettiarachchi1 , Hemalika T.K. Abeysundara3 , Thilak D.J. Abeysekara1 , Abdul Wazil4 , Saman Rathnayake5 , Jayantha Gunaratne2,6 and Nishantha Nanayakkara4 1 Centre for Education, Research and Training on Kidney Diseases (CERTKiD), Faculty of Medicine, University of Peradeniya,
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Prospective Biopsy-Based Study of CKD of Unknown Etiology in Sri Lanka
Shuchi Anand,1 Maria E. Montez-Rath,1 Dinuka Adasooriya,2,3 Neelakanthi Ratnatunga,4 Neeraja Kambham,5 Abdool Wazil,2 Sulcohana Wijetunge,4 Zeid Badurdeen,3 Charaka Ratnayake,2 Nishamani Karunasena,2 Stephen L. Schensul,6 Penny Valhos,7 Lalarukh Haider,8 Vivek Bhalla,1 Adeera Levin,9 Paul H. Wise,10 Glenn M. Chertow,1 Michele Barry,11 Andrew Z. Fire,5 and Nishantha Nanayakkara2,3 1 Division of Nephrology and Departments of 5
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Screening for chronic kidney disease of uncertain aetiology in Sri Lanka: usability of surrogate biomarkers over dipstick proteinuria
Samantha Ratnayake1,2*, Zeid Badurdeen1 , Nishantha Nanayakkara3 , Tilak Abeysekara1 , Neelakanthi Ratnatunga4 and Ranjith Kumarasiri5 Abstract Background: The use of dipstick proteinuria to screen Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a recently debated matter of dispute. The aim of this study was to assess the suitability of biomarkers:
Epidemiology, molecular, and genetic methodologies to evaluate causes of CKDu around the world: report of the Working Group from the ISN International Consortium of Collaborators on CKDu
Shuchi Anand1 , Ben Caplin2 , Marvin Gonzalez-Quiroz2,3 , Stephen L. Schensul4 , Vivek Bhalla1 , Xavier Parada5 , Nishantha Nanayakkara6 , Andrew Fire1 , Adeera Levin7 and David J. Friedman8 , on behalf of International Society of Nephrology’s International Consortium of Collaborators on Chronic Kidney Disease of Unknown Etiology (i3C)9 1 School of Medicine,