Research Publications

Comparison of biochemical characteristics between an endemic and a nonendemic area for CKDu Sri Lanka

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Comparison of biochemical characteristics between an endemic and a nonendemic area for CKDu Sri Lanka. A Medagedara1, Pasan Hewavitharane2, Rohana Chandrajith3, Hemalika T K. Abeysundara4, RO Thatil5, S Thennakoon6, Buddhisha Mahanama2, N Weerasuriya7, A Thilakarathne7, Nishantha Nanayakkara2 1 Center for Research, National Hospital, Kandy; Department of Fundamentals of Nursing, Faculty of Nursing, University of Colombo, […]

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Challenges and opportunities in interventions for chronic kidney disease of unknown origin (CKDu): report from the International Society of Nephrology Consortium of Collaborators on CKDu

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Challenges and opportunities in interventions for chronic kidney disease of unknown origin (CKDu): report from the International Society of Nephrology Consortium of Collaborators on CKDu Brendan Smyth1,2 , Jason Glaser3 , Jaime Butler-Dawson4,5 , Nishantha Nanayakkara6 , David H. Wegman3,7 , Shuchi Anand8 and Adeera Levin9 1 National Health and Medical Research Council (NHMRC) Clinical

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Early ultrastructural changes in biopsies from patients with symptomatic CKDu (Sym-CKDu)

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Christoph Daniel, Prof.1 ; Philipp Enghard, PD2 ; Neelakanthi Ratnatunga, Prof.3  ; Sulochana Wijetunge, Prof. 3 ; Wazil AWM, MD7 ; Christian Zwiener, Prof. 4 ; Johannes A.C. Barth, Prof.5 ; Rohana Chandrajith, Prof.6 ; Monika Klewer1 ; Kai-Uwe Eckhardt, Prof.2 , Kerstin Amann, Prof.1 ; Paul Freund, MD2 , Shakila Premarathne8 , W.D.R.N. Pushpakumara,

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Origin of Groundwater

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Origin of Groundwater Groundwater is the water which established in the geological formations (Fractures, Fissures, Pore Spaces) in the underground. Those groundwater bearing formations are called as Aquifers in Geology. However, groundwater copies the surface topography; Mostly groundwater flows from high pressure to low pressure (pressure gradients) fracture paths. Generally, groundwater of the world is

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Assessment of dietary macronutrient and micronutrient intake among haemodialysis patients in Sri Lanka

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NADUNI ERANDIKA1, NISHANTHA NANAYAKKARA1, LALANI YATAWARA2 1National Hospital-Kandy, Sri Lanka 2Faculty of Allied Health Sciences, University of Peradeniya, Kandy, Sri Lanka Background: Malnutrition is very common among haemodialysis (HD) patients. Aim: We aimed to assess the macronutrient and micronutrient intake and determined the association between nutritional intake and socio-economic status among HD patients. Methods: This

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Predictive Modeling

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Utilizing predetermined outcomes to develop, process, and validate models is known as predictive modelling. To develop, process, and evaluate a model that can be used to predict future outcomes, predictive modelling is the process of employing known findings. It is an instrument used in predictive analytics, a data mining technique that seeks to provide an

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Magic Mushrooms

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Magic mushrooms are a variety of naturally occurring mushrooms that contain Psilocybin. Psylocibin is a psychedelic drug that can affect all the senses of a person and can cause hallucinating effects. Psilocybin in magic mushrooms get converted to Psilocin upon digestion, which can cause psychoactive effects. The appearance of magic mushrooms look much similar to

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Evaluating Serum RBP4 as an Auxiliary Biomarker for CKDu Diagnosis

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Hannah L. F. Swa 1,†,‡,Buddhi N. T. Fernando 2,†,Shakila Premarathna 3,Asfa Alli-Shaik 1,Zeid Badurdeen 3,Jayantha Gunarathna 1,4 and Nishantha Nanayakkara 3,* 1 Translational Biomedical Proteomics Group, Institute of Molecular & Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore 138632, Singapore 2 Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of

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Body composition in lupus nephritis patients

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Duminda B. Basnayake1*, Naduni H. Erandika1, Hashan K. Amarathunga2, Ayesha A. Nayanamali1, Jayamini Pathiraja2, Rangi Kandane-Rathnayake3, Abdul W. M. Wazil1, Nishantha Nanayakkara1, Kushan T. Thennakoon1, Inoka M. Chathurani1, Ruwina A. Deepani1, Buddhika A. Wijayawickrama1 1Department of Nephrology and Renal Transplant, 2Department of Nutritional Medicine, National Hospital Kandy, Sri Lanka, 3School of Clinical Sciences at Monash

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