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Socio-economic determinants of Chronic Kidney Diseases of uncertain aetiology (CKDu)

  Introduction: – Presents the background and context of CKDu in Sri Lanka and globally. Highlights that CKDu is increasing in Uva Province but socio-economic risk factors are unknown. – Concisely states the study objectives to identify socio-economic risk factors for CKDu in Uva Province using statistical models. Methods: – Appropriate cross-sectional study design with […]

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Critical review of the article on ‘Study of the nutritional status of end-stage renal disease patients on maintenance hemodialysis in Hawary Kidney center and nephrology unit at Benghazi Medical Center’

Citation: Elramli, S. S. (2022). Study of the nutritional status of end-stage renal disease patients on maintenance hemodialysis in Benghazi. Clinical Medicine Insights, 3(1), 268-277 Introduction The aim of this cross-sectional study was to determine the prevalence of nutritional deficiencies, assess the association between nutritional status and hemodialysis, and identify the effects of patient factors

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Critical review of the article on ‘Study of the nutritional status of end-stage renal disease patients on maintenance hemodialysis in Hawary Kidney center and nephrology unit at Benghazi Medical Center’ Read More »

A critical review on research article “Evolution of immune genes is associated with the Black Death”

Evolution of immune genes is associated with the Black Death Jennifer Klunk, Tauras P. Vilgalys, Christian E. Demeure, Xiaoheng Cheng, Mari Shiratori, Julien Madej, Rémi Beau, Derek Elli, Maria I. Patino, Rebecca Redfern, Sharon N. DeWitte, Julia A. Gamble, Jesper L. Boldsen, Ann Carmichael, Nükhet Varlik, Katherine Eaton, Jean-Christophe Grenier, G. Brian Golding, Alison Devault,

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Critiquing “Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka”

Introduction This paper by Nanayakkara et al. investigates potential genetic factors associated with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka. CKDu is becoming increasingly prevalent in certain provinces of Sri Lanka, but its exact causes remain unknown. Given familial clustering observed in CKDu patients, the authors hypothesized there may be genetic susceptibility

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Critiquing “Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka” Read More »

Revolutionizing healthcare: the role of artificial intelligence in clinical practice

Introduction The article “Revolutionizing healthcare: the role of artificial intelligence in clinical practice” by Alowais et al., published in BMC Medical Education in 2023, reviews the current state of artificial intelligence (AI) in clinical practice, including its potential applications in disease diagnosis, treatment selection, and patient engagement. It also explores the associated challenges, such as

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Microplastics in the Oceans: Current Levels and Future Projections

Recent studies have reported the presence of pelagic plastic fragments with diameters <5 mm in the open oceans including polar waters, marginal seas, and coastal waters. Importantly, micro plastics might act as a transport vector of chemical pollutants into the marine ecosystem, due to the absorption of pollutants onto their surfaces. Methodology The researchers conducted surveys

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Genome-Wide Association Study on Genetic Variants for Kidney Function and Chronic Kidney Disease – A Summary

This scientific paper significantly advanced understanding of genetic contributions to kidney function and disease. Here, I summarize key aspects of their rationale, methods, results, and implications. Their rigorous findings provide new insights into kidney biology and the genomics of CKD susceptibility. Introduction The introduction provides a clear background and rationale for conducting this genome-wide association

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Kidney Stones: A Potential Indicator of Fracture Risk in Chronic Kidney Disease

Introduction This study investigates the association between kidney stones and the risk of osteoporotic fracture in patients with chronic kidney disease (CKD). The introduction provides background on how CKD patients have a higher risk of osteoporotic fracture compared to the general population, and how bone mineral density alone has limitations in predicting fracture risk. The

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“Sleep duration and brain structure: a population-based study”

Introduction The research paper “Sleep duration and brain structure: a population-based study” by Fjell et al., published in Nature Human Behaviour in 2023, investigates the relationship between self-reported sleep duration and brain volume, using data from about 51,000 individuals. The authors claim that their study is the largest and most comprehensive analysis of this topic

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Critical review of the article on ‘Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings’

Citation: Miri, M. M., Ramezani-Binabaj, M., Inanloo, S. H., Barzegar Bafrouei, M., Sefidbakht, S., & Yahyazadeh, S. R. (2023). Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings. Translational Research in Urology, 5(3), 121-127. doi: 10.22034/tru.2023.407821.1154 Introduction The main aim of investigators in this study was to identify predictive

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