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Review of “Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function”

Introduction and Background: The introduction provides a comprehensive overview of the significance of proteinuria, its causes, and the role of cubilin in protein reabsorption by the proximal tubules. It effectively summarizes the existing knowledge on the link between CUBN mutations and Imerslund-Gräsbeck syndrome (IGS) and proteinuria. Study Design and Methods The authors have utilized three […]

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Application effect of an artificial intelligence-based fundus screening system: evaluation in a clinical setting and population screening

Introduction: – Ocular fundus abnormalities like diabetic retinopathy (DR), age-related macular degeneration (ARMD), retinal vein occlusion (RVO), and pathological myopia (PM) are major causes of blindness worldwide. – Early detection is crucial for preventing irreversible vision loss from these conditions. – AI systems based on fundus imaging like color fundus photography (CFP) have potential for

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Critical review of the article on ‘Using implantation biopsies as a surrogate to evaluate selection criteria for living kidney donors’

Citation: Chauhan, A., Diwan, T. S., Palacios, C. R. F., Dean, P. G., Heimbach, J. K., Chow, G. K., … & Stegall, M. D. (2013). Using implantation biopsies as a surrogate to evaluate selection criteria for living kidney donors. Transplantation, 96(11), 975-980. Introduction In this study, they analyzed histologic characteristics of kidney biopsies obtained at

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“Detailed Review of Chronic Kidney Disease”

Abstract: This review examines a comprehensive overview of chronic kidney disease (CKD) published by Kakitapalli et al. in 2020. The original article covers the epidemiology, risk factors, diagnosis, management, and prevention of CKD. This review analyzes the key findings and contributions of the article to the current understanding of CKD. Introduction: Chronic kidney disease is

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Critical review of the paper titled “ A Graph Database Approach for Temporal Modeling of Disease Progression”

Memarzadeh, H., Ghadiri, N., & Parikhah Zarmehr, S. (2018). A graph database approach for temporal modeling of disease progression. 2018 8th International Conference on Computer and Knowledge Engineering (ICCKE) (pp. 293-297). IEEE. Introduction The paper by Memarzadeh et al. proposes using a graph database (Neo4j) for temporal modeling and analysis of disease progression, with a

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Critical review of “Population exposure to multiple air pollutants and its compound episodes in Europe”

The article “Population exposure to multiple air pollutants and its compound episodes in Europe” published in Nature Communications, in 2024 explores population exposure to various air pollutants and the occurrence of compound pollution episodes. In this review will analyze the strengths and weaknesses of the research, while also suggesting potential areas for future exploration. Strengths

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Critical review of the article on ‘Time-zero renal biopsy in living kidney transplantation: a valuable opportunity to correlate pre-donation clinical data with histological abnormalities’

Citation: Mancilla, E., Avila-Casado, C., Uribe-Uribe, N., Morales-Buenrostro, L. E., Rodríguez, F., Vilatoba, M., … & Alberú, J. (2008). Time-zero renal biopsy in living kidney transplantation: a valuable opportunity to correlate predonation clinical data with histological abnormalities. Transplantation, 86(12), 1684-1688. Introduction In this study, they analyzed histologic characteristics of kidney biopsies obtained at the time

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Milk Fat Biomarkers and Risk of Myocardial Infarction: A Contradictory Perspective, a critical review of the research article by Warensjo et al. (2010)

Biomarkers of milk fat and the risk of myocardial infarction in men and women: a prospective, matched case-control study by Warensjo et al. (2010) provide great insights into biomarkers of milk fat and its correlation of the risk of MI. The Research Approach The objective of this prospective case-control study was to investigate the association

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Ultra-Processed Food Exposure and Adverse Health Outcomes

Introduction: Ultra-processed foods (UPFs) have become ubiquitous in modern diets, characterized by their high levels of chemical additives, sugars, fats, and minimal whole-food content. The Nova food classification system categorizes UPFs as the most heavily processed category, distinct from minimally processed or unprocessed foods. Given their prevalence and potential impact on health, understanding the associations

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A Collaborative Effort: How an ISN Sister Renal Centers Partnership Transformed Peritoneal Dialysis Care in Sri Lanka

An ISN Sister Renal Centers partnership between Kandy Teaching Hospital (KTH) in Sri Lanka and Stanford University (affiliated with Santa Clara Valley Medical Center) has brought about a substantial transformation in the kidney care landscape in the country, elevating continuous ambulatory peritoneal dialysis (CAPD) care delivery, training, and patient education across the nation. Dr. Anjali

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