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Tubulointerstitial nephropathy is the predominant finding in men in a review of more than 3000 renal biopsies over a 10-year period from Sri Lanka.

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Jennifer Pett1,2, Christine Linhart1*, Nicholas Osborne1,3*, Stephen Morrell1, Mohammed Fahim4,5, John Knight1,2, Shakila Premaranthne6,7, A. W. M. Wazil8, Neelakanthi Ratnatunga9, Sulcochana Wijethunga9, Shenal Thalgahagoda10, Zoltan Endre5,11, Richard Taylor1 and Nishantha Nanayakkara8   1 School of Population Health, University of New South Wales, UNSW, Sydney, Australia. 2 The George Institute for Global Health, Sydney, Australia. 3 […]

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Tubulointerstitial nephropathy is the predominant finding in men in a review of more than 3000 renal biopsies over a 10-year period from Sri Lanka. Read More »

Screening of Micro-organic Compounds in Groundwater from Areas with Chronic Kidney Disease of Unclear Aetiology (CKDu) in the Dry Zone of Sri Lanka

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Rohana Chandrajith1, Christian Zwiener2, Christoph Daniel3, Kerstin Amann3, Nishantha Nanayakkara4, Johannes A. C. Barth5 1 Department of Geology, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka. 2 Environmental Analytical Chemistry, Department of Geosciences, Eberhard-Karls-University Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany. 3 Institute of Pathologe, Department of Nephropathology, Friedrich-Alexander-Universität (FAU), Erlangen Nürnberg Krankenhausstr. 8-10, 91054

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Screening of Micro-organic Compounds in Groundwater from Areas with Chronic Kidney Disease of Unclear Aetiology (CKDu) in the Dry Zone of Sri Lanka Read More »

Review of “Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function”

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Introduction and Background: The introduction provides a comprehensive overview of the significance of proteinuria, its causes, and the role of cubilin in protein reabsorption by the proximal tubules. It effectively summarizes the existing knowledge on the link between CUBN mutations and Imerslund-Gräsbeck syndrome (IGS) and proteinuria. Study Design and Methods The authors have utilized three

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Application effect of an artificial intelligence-based fundus screening system: evaluation in a clinical setting and population screening

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Introduction: – Ocular fundus abnormalities like diabetic retinopathy (DR), age-related macular degeneration (ARMD), retinal vein occlusion (RVO), and pathological myopia (PM) are major causes of blindness worldwide. – Early detection is crucial for preventing irreversible vision loss from these conditions. – AI systems based on fundus imaging like color fundus photography (CFP) have potential for

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“Detailed Review of Chronic Kidney Disease”

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Abstract: This review examines a comprehensive overview of chronic kidney disease (CKD) published by Kakitapalli et al. in 2020. The original article covers the epidemiology, risk factors, diagnosis, management, and prevention of CKD. This review analyzes the key findings and contributions of the article to the current understanding of CKD. Introduction: Chronic kidney disease is

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Review of Urinary proteomics in chronic kidney disease: diagnosis and risk of progression beyond albuminuria

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Summary This study examined the utility of urinary proteomics analysis using capillary electrophoresis coupled to mass spectrometry (CE-MS) for diagnosing chronic kidney disease (CKD) and predicting rapid kidney function decline. The authors analyzed urine samples from 18 CKD patients (including those with hypertensive nephropathy) and 17 healthy controls. They found that a urinary proteomic classifier

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Association Between Occupational Heat Stress and Kidney Disease Among 37,816 Workers in the Thai Cohort Study (TCS)

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Introduction – Provides background on the rising issue of heat stress due to climate change and its potential health impacts, including kidney disease. – Highlights the lack of studies examining the association between occupational heat stress and kidney disease, particularly in tropical countries like Thailand. – Outlines the objectives of the study to examine this

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The relationship between hydronephrosis severity on ultrasound and kidney stone size

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Introduction Kidney stones are a common urologic condition, with an increasing incidence and prevalence globally. Non-contrast computed tomography (CT) is frequently used in emergency departments to evaluate suspected kidney stones, given its high accuracy for detecting the presence, size and location of stones. However, ultrasound is advantageous due to lower cost, lack of ionizing radiation,

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Critical Review of Glutathione level and glutathione reductase activity in serum of coronary heart disease patients

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This study by Zuzak et al. investigates glutathione reductase (GR) activity and glutathione (GSH) levels in the serum of patients with different stages of coronary heart disease (CHD). The authors enrolled 20 patients, each with stable angina, unstable angina, and myocardial infarction, along with 20 healthy controls. Blood samples are collected before cardiac catheterization. GR

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Critical Review of Near-Death Experiences and the Temporal Lobe by Britton and Bootzin (2004)

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Summary of the Study This study investigated the hypothesis that near-death experiences are associated with altered temporal lobe functioning. Their study compared 23 individuals reporting transcendental near-death experiences during life-threatening events with 20 healthy control subjects on measures of temporal lobe functioning, including EEG during an overnight sleep study, questionnaires on temporal lobe symptoms, and

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