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A critical review on research article “Evolution of immune genes is associated with the Black Death”

Evolution of immune genes is associated with the Black Death Jennifer Klunk, Tauras P. Vilgalys, Christian E. Demeure, Xiaoheng Cheng, Mari Shiratori, Julien Madej, Rémi Beau, Derek Elli, Maria I. Patino, Rebecca Redfern, Sharon N. DeWitte, Julia A. Gamble, Jesper L. Boldsen, Ann Carmichael, Nükhet Varlik, Katherine Eaton, Jean-Christophe Grenier, G. Brian Golding, Alison Devault, […]

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Critiquing “Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka”

Introduction This paper by Nanayakkara et al. investigates potential genetic factors associated with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka. CKDu is becoming increasingly prevalent in certain provinces of Sri Lanka, but its exact causes remain unknown. Given familial clustering observed in CKDu patients, the authors hypothesized there may be genetic susceptibility

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Critiquing “Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka” Read More »

Revolutionizing healthcare: the role of artificial intelligence in clinical practice

Introduction The article “Revolutionizing healthcare: the role of artificial intelligence in clinical practice” by Alowais et al., published in BMC Medical Education in 2023, reviews the current state of artificial intelligence (AI) in clinical practice, including its potential applications in disease diagnosis, treatment selection, and patient engagement. It also explores the associated challenges, such as

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Microplastics in the Oceans: Current Levels and Future Projections

Recent studies have reported the presence of pelagic plastic fragments with diameters <5 mm in the open oceans including polar waters, marginal seas, and coastal waters. Importantly, micro plastics might act as a transport vector of chemical pollutants into the marine ecosystem, due to the absorption of pollutants onto their surfaces. Methodology The researchers conducted surveys

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Genome-Wide Association Study on Genetic Variants for Kidney Function and Chronic Kidney Disease – A Summary

This scientific paper significantly advanced understanding of genetic contributions to kidney function and disease. Here, I summarize key aspects of their rationale, methods, results, and implications. Their rigorous findings provide new insights into kidney biology and the genomics of CKD susceptibility. Introduction The introduction provides a clear background and rationale for conducting this genome-wide association

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Kidney Stones: A Potential Indicator of Fracture Risk in Chronic Kidney Disease

Introduction This study investigates the association between kidney stones and the risk of osteoporotic fracture in patients with chronic kidney disease (CKD). The introduction provides background on how CKD patients have a higher risk of osteoporotic fracture compared to the general population, and how bone mineral density alone has limitations in predicting fracture risk. The

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“Sleep duration and brain structure: a population-based study”

Introduction The research paper “Sleep duration and brain structure: a population-based study” by Fjell et al., published in Nature Human Behaviour in 2023, investigates the relationship between self-reported sleep duration and brain volume, using data from about 51,000 individuals. The authors claim that their study is the largest and most comprehensive analysis of this topic

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Critical review of the article on ‘Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings’

Citation: Miri, M. M., Ramezani-Binabaj, M., Inanloo, S. H., Barzegar Bafrouei, M., Sefidbakht, S., & Yahyazadeh, S. R. (2023). Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings. Translational Research in Urology, 5(3), 121-127. doi: 10.22034/tru.2023.407821.1154 Introduction The main aim of investigators in this study was to identify predictive

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Describing Natural History and Exploring Risk Factors for Kidney Function Decline in Persons With CKD of Uncertain Etiology in Sri Lanka.

Pasan Hewavitharana1,2,11, Stephen Schensul3 , Edison Lee4 , Maria Montez-Rath4 , Sachintha Senarathne5 , Sai Liu4 , Kaitlin Harold4 , Santhushya Hewapathiranage1 , Naduni Erandika1 , Hemalika T.K. Abeysundara6 , Xue Yu4 , Vivek Bhalla4 , Andrew Fire7 , Adeera Levin8 , Shuchi Anand4 , Penny Vlahos9,11, Rohana Chandrajith5,11 and Nishantha Nanayakkara1,10,11 1 Center for

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Describing Natural History and Exploring Risk Factors for Kidney Function Decline in Persons With CKD of Uncertain Etiology in Sri Lanka. Read More »

The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation.

The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation. Kalpa Dheerasekara 1, Rekshi Tharanga 1, Lakmali Rajamanthri 2, Abdul Wazil 3, Nishantha Nanayakkara 3, Rohitha Muthugala 2 1Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka. 2Department of Virology,

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The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation. Read More »

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