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Critical review of the paper titled “Early renal damage among children living in the region of highest burden of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka”

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Agampodi, S. B., Amarasinghe, G. S., Naotunna, P. G. C. R., Jayasumana, C. S., & Siribaddana, S. H. (2018). Early renal damage among children living in the region of the highest burden of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka. BMC Nephrology, 19, 115. DOI: 10.1186/s12882-018-0911-8 Introduction The study conducted by Agampodi […]

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Critical Review of “Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work”

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Introduction The article “Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work” by Westbrook et al., published in Science in 2020, investigates the role of dopamine in modulating the subjective value of cognitive effort and the willingness to exert cognitive control. The authors claim that their study is the first to

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Critical Review of Glutathione level and glutathione reductase activity in serum of coronary heart disease patients

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This study by Zuzak et al. investigates glutathione reductase (GR) activity and glutathione (GSH) levels in the serum of patients with different stages of coronary heart disease (CHD). The authors enrolled 20 patients, each with stable angina, unstable angina, and myocardial infarction, along with 20 healthy controls. Blood samples are collected before cardiac catheterization. GR

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A critical review on the research article “Sound healing reduces generalized anxiety during the pandemic: A feasibility study”

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“Sound healing reduces generalized anxiety during the pandemic: A feasibility study” presents a feasibility study on the effectiveness of a virtually-delivered, biofield-based sound healing treatment to reduce anxiety for individuals meeting criteria for Generalized Anxiety Disorder. The study was conducted virtually via Zoom during the SARS-CoV-2 Pandemic. Fifteen participants with moderate to high levels of

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Critical Review of CLINICAL COURSE OF DENGUE FEVER AND ITS IMPACT ON RENAL FUNCTION IN RENAL TRANSPLANT RECIPIENTS AND PATIENTS WITH CHRONIC KIDNEY DISEASE

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The authors conducted an observational study to compare the clinical course and impact on renal function of dengue fever in renal transplant recipients, patients with chronic kidney disease (CKD), and patients with normal baseline renal function. The study was done during a dengue epidemic in India and included 12 transplant recipients, 22 CKD patients, and

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Critical Review of Near-Death Experiences and the Temporal Lobe by Britton and Bootzin (2004)

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Summary of the Study This study investigated the hypothesis that near-death experiences are associated with altered temporal lobe functioning. Their study compared 23 individuals reporting transcendental near-death experiences during life-threatening events with 20 healthy control subjects on measures of temporal lobe functioning, including EEG during an overnight sleep study, questionnaires on temporal lobe symptoms, and

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Critical review of the paper titled “Longitudinal Progression Trajectory of GFR Among Patients With CKD”

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Li, L., Astor, B. C., Lewis, J., Hu, B., Appel, L. J., Lipkowitz, M. S., … & Greene, T. H. (2012). Longitudinal Progression Trajectory of GFR Among Patients With CKD. American Journal of Kidney Diseases, 59(4), 504–512. Introduction The study by Li et al. aimed to investigate the longitudinal trajectories of estimated glomerular filtration rate

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A critical review on the article “Smoking changes adaptive immunity with persistent effects”

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The article titled “Smoking has long-term effects on the immune system” published in Nature on February 14, 2024, presents a comprehensive study on the impact of smoking on the immune system. The research was conducted by a team of scientists at the Institut Pasteur using the Milieu Intérieur cohort of 1,000 healthy volunteers. The study’s

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Association between pesticide exposure and chronic kidney disease of uncertain etiology in agricultural worker populations: A systematic review and meta-analysis

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This proposed systematic review would compile evidence on the relationship between pesticide exposure and CKDu risk specifically in agricultural worker groups through meta-analysis of observational studies. It can evaluate the strength of association and sources of heterogeneity across different geographical regions and help identify research gaps to drive priorities for future epidemiological research on environmental/occupational

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Inside the bold mission to map every immune system in the world

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Introduction The article “Inside the bold mission to map every immune system in the world” by James Lloyd, published in BBC Science Focus Magazine in January 2024, discusses the aims and challenges of the Human Immunome Project (HIP), a global initiative that seeks to create a digital library of the immune system of every human

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