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Articles

Critical Review of Glutathione level and glutathione reductase activity in serum of coronary heart disease patients

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This study by Zuzak et al. investigates glutathione reductase (GR) activity and glutathione (GSH) levels in the serum of patients with different stages of coronary heart disease (CHD). The authors enrolled 20 patients, each with stable angina, unstable angina, and myocardial infarction, along with 20 healthy controls. Blood samples are collected before cardiac catheterization. GR […]

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Critical Review of Near-Death Experiences and the Temporal Lobe by Britton and Bootzin (2004)

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Summary of the Study This study investigated the hypothesis that near-death experiences are associated with altered temporal lobe functioning. Their study compared 23 individuals reporting transcendental near-death experiences during life-threatening events with 20 healthy control subjects on measures of temporal lobe functioning, including EEG during an overnight sleep study, questionnaires on temporal lobe symptoms, and

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Association between pesticide exposure and chronic kidney disease of uncertain etiology in agricultural worker populations: A systematic review and meta-analysis

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This proposed systematic review would compile evidence on the relationship between pesticide exposure and CKDu risk specifically in agricultural worker groups through meta-analysis of observational studies. It can evaluate the strength of association and sources of heterogeneity across different geographical regions and help identify research gaps to drive priorities for future epidemiological research on environmental/occupational

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Inside the bold mission to map every immune system in the world

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Introduction The article “Inside the bold mission to map every immune system in the world” by James Lloyd, published in BBC Science Focus Magazine in January 2024, discusses the aims and challenges of the Human Immunome Project (HIP), a global initiative that seeks to create a digital library of the immune system of every human

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Critical review of the article on ‘Limited Health Literacy in Advanced Kidney Disease’

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Citation: Taylor, D. M., Bradley, J. A., Bradley, C., Draper, H., Johnson, R., Metcalfe, W., … & ATTOM Investigators. (2016). Limited health literacy in advanced kidney disease. Kidney international, 90(3), 685-695. Introduction This study aimed to determine the prevalence of limited health literacy and its associations in patients with advanced kidney disease in the UK.

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Socio-economic determinants of Chronic Kidney Diseases of uncertain aetiology (CKDu)

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  Introduction: – Presents the background and context of CKDu in Sri Lanka and globally. Highlights that CKDu is increasing in Uva Province but socio-economic risk factors are unknown. – Concisely states the study objectives to identify socio-economic risk factors for CKDu in Uva Province using statistical models. Methods: – Appropriate cross-sectional study design with

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Kidney Stones: A Potential Indicator of Fracture Risk in Chronic Kidney Disease

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Introduction This study investigates the association between kidney stones and the risk of osteoporotic fracture in patients with chronic kidney disease (CKD). The introduction provides background on how CKD patients have a higher risk of osteoporotic fracture compared to the general population, and how bone mineral density alone has limitations in predicting fracture risk. The

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Critical review of the article on ‘Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings’

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Citation: Miri, M. M., Ramezani-Binabaj, M., Inanloo, S. H., Barzegar Bafrouei, M., Sefidbakht, S., & Yahyazadeh, S. R. (2023). Investigation of Predictive Factors for Function of Transplanted Kidney Graft Based on Zero-Time Biopsy Findings. Translational Research in Urology, 5(3), 121-127. doi: 10.22034/tru.2023.407821.1154 Introduction The main aim of investigators in this study was to identify predictive

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Describing Natural History and Exploring Risk Factors for Kidney Function Decline in Persons With CKD of Uncertain Etiology in Sri Lanka.

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Pasan Hewavitharana1,2,11, Stephen Schensul3 , Edison Lee4 , Maria Montez-Rath4 , Sachintha Senarathne5 , Sai Liu4 , Kaitlin Harold4 , Santhushya Hewapathiranage1 , Naduni Erandika1 , Hemalika T.K. Abeysundara6 , Xue Yu4 , Vivek Bhalla4 , Andrew Fire7 , Adeera Levin8 , Shuchi Anand4 , Penny Vlahos9,11, Rohana Chandrajith5,11 and Nishantha Nanayakkara1,10,11 1 Center for

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The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation.

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The pattern of cytomegalovirus replication in post-renal transplant recipients with pre-emptive therapy strategy during the 1st year of post-transplantation. Kalpa Dheerasekara 1, Rekshi Tharanga 1, Lakmali Rajamanthri 2, Abdul Wazil 3, Nishantha Nanayakkara 3, Rohitha Muthugala 2 1Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka. 2Department of Virology,

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