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Articles

“The COVID-19 pandemic: consequences for nephrology”

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Source – https://doi.org/10.3390/biomedicines11030926 Introduction The article by Annette Bruchfeld, published in Nature Reviews Nephrology (February 2021) provides a timely analysis of COVID-19’s impact on nephrology. The article effectively summarises early research findings from 2020 regarding the relationship between COVID-19 and kidney disease. This review will evaluate the article’s scientific merits, methodological approach, findings, limitations, and […]

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Critical review of the article on ‘Patient Management and Clinical Outcomes Associated with a Recorded Diagnosis of Stage 3 Chronic Kidney Disease: The REVEAL-CKD Study’

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Citation: Tangri, N., Peach, E. J., Franzén, S., Barone, S., & Kushner, P. R. (2023). Patient management and clinical outcomes associated with a recorded diagnosis of stage 3 chronic kidney disease: the REVEAL-CKD study. Advances in Therapy, 40(6), 2869-2885. Introduction Chronic kidney disease (CKD) is a major public health concern [1], and its prevalence is

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Critical Review: Sri Lanka’s Mental Health Crisis – Underfunding, Stigma, and Service Gaps

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Three main issues affect mental health in Sri Lanka: limited finances, much stigma, and poor services, particularly in rural areas.  Despite having effective policies, inequalities are still generated by inefficiencies and cultural factors.  Approximately 13.3% of people experience untreated mental illness as a result (Mental Health in Sri Lanka A Summary – Join Health, n.d.;

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Potential diagnostic biomarkers for chronic kidney disease of unknown etiology (CKDu) in Sri Lanka: a pilot study

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Critical Review Introduction The study by Sayanthooran et al. (2017) explores a significant public health issue in Sri Lanka—chronic kidney disease of unknown etiology (CKDu)—which predominantly affects farming communities in dry zones. Unlike typical CKD cases, which are often linked to diabetes or hypertension, CKDu lacks a clearly defined cause. The researchers aimed to identify

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Critical review of “Artificial Intelligence as a Replacement for Animal Experiments in Neurology: Potential, Progress, and Challenges” by Thorsten Rudroff

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  Thorsten Rudroff’s 2024 perspective article explores the transformative potential of artificial intelligence (AI) to supplant animal experimentation in neurology. The article offers a comprehensive and optimistic overview of emerging AI methodologies, including brain organoids, computational modeling, and machine learning, positing them as superior alternatives to traditional animal-based research. While the article is rich in

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Distinctive Patterns of Trace Elements in Chronic Kidney Disease of Uncertain Etiology: Comparative Analysis Across Multiple Control Groups

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Buddhi N. T. Fernando 1,2 ,Nishantha Nanayakkara 3 ,Rohana Chandrajith 4 ,Hemalika T. K. Abeysundara 5 and Dulanjali Herath 6 1 Centre for Education, Research and Training on Kidney Diseases, University of Peradeniya, Peradeniya 20400, Sri Lanka 2 Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Ruhuna, Walahanduwa, Galle 80000, Sri

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Making the Case for New Donor Selection Criteria in CKDu Endemic Areas: A Crucial Step for Sustainable Kidney Transplantation in Sri Lanka.

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Naduni Erandika BSc,1 Rajitha Abeysekera MD,2 Sulochana Wijetunge MD,3 Hemalika Abeysundara PhD,4 Abdul Wazil MD,1 Neelakanthi Ratnatunga PhD,3 and Nishantha Nanayakkara MD1   CHRONIC KIDNEY DISEASE PREVALENCE IN SRI LANKA. Sri Lanka is an island nation of 21 million people with a high burden of chronic kidney disease (CKD) due to diabetes and hypertension.1 CKD

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Making the Case for New Donor Selection Criteria in CKDu Endemic Areas: A Crucial Step for Sustainable Kidney Transplantation in Sri Lanka. Read More »

Meet an Expert – Session 1

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We were honored to host Professor Jayantha Gunaratne, Senior Principal Investigator at IMCB A*STAR Singapore and Associate Professor at NUS School of Medicine, for an exceptional ‘Meet an Expert’ session. Professor Gunaratne shared groundbreaking insights on proteomics and its biomedical applications, fostering valuable discussions with our medical professionals. Special thanks to our Director and all

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Geoenvironmental Determinants Influencing Chronic Kidney Disease of Unknown Etiology in the dry zone of Sri Lanka: a study based on a cohort of at-risk communities

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Dhananjalee Mahalekam, Ishara Athauda, Penny Vlahos, Shuchi Anand, Nishantha Nanayakkara, Rohana Chandrajith   Abstract Chronic kidney disease of unknown origin (CKDu) has emerged as a serious health risk for farming communities in remote semi-arid lowland regions of Sri Lanka, with geoenvironmental factors widely believed to be associated with the etiology. Although numerous case–control studies have

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Spatial Analysis of Chronic Kidney Disease of Unknown Aetiology (CKDu) Prevalence in Badulupura Village, Sri Lanka

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B. S. Marasinghe, W. A. U. Vitharana, R. Chandrajith, N. Nanayakkara, H. P. U. Fonseka   Abstract This study investigated spatial patterns of chronic kidney disease of unknown aetiology (CKDu) patients in Badulupura village. The analysis utilized published locational data for all households, including households affected by CKDu, and all wells used by CKDu-affected patients

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